منابع مشابه
Bioengineering for Organ Transplantation: Progress and Challenges.
Organ transplantation can offer a curative option for patients with end stage organ failure. Unfortunately the treatment is severely limited by the availability of donor organs. Organ bioengineering could provide a solution to the worldwide critical organ shortage. The majority of protocols to date have employed the use of decellularization-recellularization technology of naturally occurring ti...
متن کاملTransplantation of embryonic kidneys.
The number of kidney allotransplants performed per year is limited by the availability of human donor organs. Xenotransplantation of a vascularized organ, such as the kidney, as an alternative to allotransplantation presents formidable immunological challenges. One novel solution to this conundrum is to use embryonic kidneys taken from animal donors early during organogenesis when metanephroi c...
متن کاملRenal bioengineering with scaffolds generated from rat and pig kidneys.
BACKGROUND Chronic kidney disease (CKD) is a global public health issue with an estimated prevalence of 8-16% worldwide. End-stage renal disease eventually develops every year in 0.15-0.2% of patients with overt CKD, and renal replacement therapy (RRT) with dialysis or transplantation is required. Although approximately 2 million people worldwide are currently on RRT to sustain life, this likel...
متن کاملMetallothionein in rabbit kidneys preserved for transplantation.
Thirteen rabbits were given repeated cadmium injections to achieve cadmium concentrations in kidney cortex ranging from 0.05 to 1 mmole Cd/kg wet weight. Another four animals served as controls. One kidney from each animal was frozen directly to -70 degrees C whereas the other kidney was kept for 24 hr at +4 degrees C in a preservative (Sachs' solution) to simulate conditions for preservation o...
متن کاملTransplantation of kidneys with tumors.
The shortage of donors in the face of the increasing number of patients wait-listed for renal transplantation has prompted several strategies including the use of kidneys with a tumor, whether found by chance on harvesting from a deceased donor or intentionally removed from a living donor and transplanted after excision of the lesion. Current evidence suggests that a solitary well-differentiate...
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ژورنال
عنوان ژورنال: Seminars in Nephrology
سال: 2014
ISSN: 0270-9295
DOI: 10.1016/j.semnephrol.2014.06.005